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Immunization
Findings in immunization reported from Z. Urry and co-researchers
April 8th, 2009
According to recent research from London, the United Kingdom, "Signaling through the TLR family of molecular pattern recognition receptors has been implicated in the induction of innate and adaptive immune responses. A role for TLR signaling in the maintenance and/or regulation of Treg function has been proposed, however its functional relevance remains unclear." "Here we have shown that TLR9 is highly expressed by human Treg secreting the antiinflammatory cytokine IL-10 induced following stimulation of blood and tissue CD3(+) T cells in the presence of 1 alpha,25-dihydroxyvitamin D3 (1 alpha 25VitD3), the active form of Vitamin D, with or without the glucocorticoid....
Source: Vaccine Weekly (2009-04-08)
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