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Malaria
Data from E.D. Putrianti et al provide new insights into malaria
April 8th, 2009
According to recent research from Berlin, Germany, "Liver-stage development of Plasmodium parasites represents a dramatic expansion phase for the malarial parasite between vector transmission and onset of the pathogenic blood-stage cycle." "Here, we report that repeated causal-prophylactic primaquine treatment of liver-stage Plasmodium parasites in rodents elicits vaccine-like protective immunity against sporozoite-induced malaria. This regimen differs fundamentally from those involving radiation-or genetically attenuated parasites, in which long-lasting immune responses are dependent on persistence of metabolically active parasites," wrote E.D. Putrianti and...
Source: Vaccine Weekly (2009-04-08)
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