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Alzheimer Disease
Research conducted at New York University has provided new information about Alzheimer disease
April 15th, 2009
"The pathogenesis of Alzheimer's disease (AD) is thought to be related to the accumulation of amyloid beta (A beta) in amyloid deposits and toxic oligomeric species. Immunomodulation is emerging as an effective means of shifting the equilibrium from A beta accumulation to clearance; however, excessive cell mediated inflammation and cerebral microhemorrhages are two forms of toxicity which can occur with this approach," scientists writing in the Journal of Neuroscience report. "Vaccination studies have so far mainly targeted the adaptive immune system. In the present study, we have stimulated the innate immune system via the Toll-like receptor 9 (TLR9) with...
Source: Vaccine Weekly (2009-04-15)
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