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Life Sciences
New life sciences study findings have been reported by P.L. Roberts and colleagues
April 15th, 2009
According to recent research from the United Kingdom, "Treatment with solvent/detergent is a widely used method for ensuring the virus safety of plasma products. In the present study, virus inactivation by a novel solvent/detergent combination, i.e." "TnBP (tri-n-butyl phosphate) and polysorbate 20 during the manufacture of the factor VIII/VWF concentrate Optivate (R) has been investigated. The inactivation of most enveloped viruses was rapid, i.e. > 5 log in 2 min, although the inactivation of vaccinia virus was slower, i.e. 4 log in 1 h. Virus inactivation was effective over a wide range of conditions, i.e. solvent/detergent concentration, protein concentration and...
Source: Vaccine Weekly (2009-04-15)
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