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Tetanus
New tetanus research has been reported by P. Mateitschuk et al
April 15th, 2009
"Tetanus toxoid is a vital primary reference material used for standardization of assays required to establish the antigenic purity of tetanus toxoid for vaccine production. Several formulations were assessed and ampouled fills of each formulation lyophilised," scientists in Potters Bar, the United Kingdom report. "The relative Lf content determined by Ramon flocculation, SRD, and ELISA assays was measured. The stability of the tetanus toxoid activity in each formulation was assessed by accelerated degradation studies. Formulations containing glycine were not suitable in flocculation tests but both sorbitol and trehalose formulations were. The trehalose/sodium chloride...
Source: Vaccine Weekly (2009-04-15)
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