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Cincinnati Children's Hospital Medical Center
Discovery of protein that reactivates herpes simplex virus helps solve medical mystery
April 15th, 2009
Research in PLoS Pathogens appears to solve a long standing medical mystery by identifying a viral protein, VP16, as the molecular key that prompts herpes simplex virus (HSV) to exit latency and cause recurrent disease. Led by researchers at Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, the landmark study points to a molecular target for designing improved HSV vaccines and treatments. It also could direct refined engineering of HSV viruses used in cancer therapy, the investigators said. The study was conducted in collaboration with the Medical Research Council Virology Unit of Glasgow,...
Source: Vaccine Weekly (2009-04-15)
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