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Vaccine Weekly

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Allergies



New allergies data have been reported by researchers at Medical University of Vienna



April 22nd, 2009

According to recent research published in the journal Allergy, "The major timothy grass pollen allergen, Phl p 1, resembles the allergenic epitopes of natural group I grass pollen allergens and is recognized by more than 95% of grass-pollen-allergic patients. Our objective was the construction, purification and immunologic characterization of a genetically modified derivative of the major timothy grass pollen allergen, Phl p 1 for immunotherapy of grass pollen allergy."

"A mosaic protein was generated by PCR-based re-assembly and expression of four cDNAs coding for Phl p 1 fragments and compared to the Phl p 1 wild-type by circular dichroism analysis,...


Source: Vaccine Weekly (2009-04-22)

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