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HIV/AIDS Co-Infection
Data on HIV/AIDS co-infection detailed by researchers at Oregon Health & Science University
April 22nd, 2009
According to recent research from the United States, "The rapid onset of massive, systemic viral replication during primary HIV or simian immunodeficiency virus (SIV) infection and the immune evasion capabilities of these viruses pose fundamental problems for vaccines that depend upon initial viral replication to stimulate effector T cell expansion and differentiation(1-5). We hypothesized that vaccines designed to maintain differentiated effector memory T cell (T-EM cell) responses(5,6) at viral entry sites might improve efficacy by impairing viral replication at its earliest stage(2), and we have therefore developed SIV protein-encoding vectors based on rhesus cytomegalovirus (RhCMV),...
Source: Vaccine Weekly (2009-04-22)
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