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Vaccine Weekly

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Life Sciences



New findings reported from Z.Y. Lv and co-authors describe advances in life sciences



April 22nd, 2009

"Researches on genes expressed in a cercarial stage-specific manner may help us understand the molecular events and functions during schistosome invasion of skin. A genomic clone encoding 8-kDa calcium-binding protein (SjCa8) specifically expressed in cercariae and skin-stage schistosomulum (transformed within 3 h) was obtained from cercariae," scientists in Guangzhou, People's Republic of China report.

"Recombinant protein was expressed in vector pET32a (+) and purified using a Ni-NTA purification system. The target protein SjCa8 was determined by matrix-assisted laser desorption/ionization time-of-flight (TOF)/TOF mass spectrometer after thrombin digestion and...


Source: Vaccine Weekly (2009-04-22)

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