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Tetanus
Data on tetanus reported by S.G.L. Quaak and co-researchers
April 22nd, 2009
"The pDERMATT (plasmid DNA encoding recombinant MART-1 and tetanus toxin fragment-c) plasmid is a novel in-house developed anti-cancer vaccine which encodes a melanoma associated epitope (Mart]) and an immuno stimulatory sequence (tetanus toxin fragment-c). The pharmaceutical development of pDERMATT necessitated the availability of an assay for the quantification and purity determination of pDERMATT active pharmaceutical ingredient (API), the produced bulk drug and its pharmaceutical dosage form," researchers in Netherlands report. "An anion-exchange liquid chromatographic method (AEX-LC) with ultraviolet (UV) detection was developed, which is based on separation on a...
Source: Vaccine Weekly (2009-04-22)
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