Campylobacter
Research on campylobacter detailed by M.A. Monteiro and co-authors
Published in Vaccine Weekly, April 22nd, 2009
According to recent research published in the journal Infection and Immunity, "The capsule polysaccharide (CPS) of Campylobacter jejuni is one of the few identified virulence determinants of this important human pathogen. Since CPS conjugate vaccines have been so effective against other mucosal pathogens, we evaluated this approach using CPSs from two strains of C. jejuni, 81-176 (HS23 and HS36 serotype complex) and CG8486 (HS4 serotype complex)."
"The CPSs of 81-176 and CG8486 were independently linked to the carrier protein CRM197 by reductive amination between an aldehyde(s), strategically created at the nonreducing end of each CPS, and accessible amines of...
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Source: Vaccine Weekly (2009-04-22)
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