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Clinical Trial Research
Researchers from University of Washington report details of new studies and findings in the area of clinical trial research
April 22nd, 2009
"Randomized clinical trials are a powerful tool for investigating causal treatment effects, but in human trials there are of ten times problems of noncompliance which standard analyses, such as the intention-to-treat or as-treated analysis, either ignore or incorporate in such a way that the resulting estimand is no longer a causal effect. One alternative to these analyses is the complier average causal effect (CACE) which estimates the average causal treatment effect among a subpopulation that would comply under any treatment assigned," scientists writing in the journal Biometrics report. "We focus on the setting of a randomized clinical trial with crossover...
Source: Vaccine Weekly (2009-04-22)
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