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Immunotherapy
Researchers from University of California, Medical Department report on findings in immunotherapy
April 29th, 2009
"Dendritic cells (DCs) are professional antigen (Ag)-presenting cells capable of inducing immune responses to turner Ags and, therefore, play a central role in the induction Of antitumor immunity. There is it large amount of evidence, however, about paucity Or tumor-associated DCs and that DCs' immunogenic functions are suppressed ill a turner environment," scientists in the United States report. "Here we describe a potent in situ vaccine targeting tumoral DCs in vivo. This vaccine comprised of an oncolytic adenovirus expressing RANTES (regulated upon activation, normally T expressed, and presumably secreted) (Ad-RANTES-E1A), enhanced tumor infiltration, and Maturation...
Source: Vaccine Weekly (2009-04-29)
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