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Vaccine Weekly

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Vaccines



Research on vaccines described by scientists at Harvard University, Department of Medicine



April 29th, 2009

Scientists discuss in 'Type I Streptococcus pneumoniae carbohydrate utilizes a nitric oxide and MHC II-dependent pathway for antigen presentation' new findings in vaccines. "Some pathogenic bacteria form thick capsules that both block immune responses through inhibition of complement deposition and phagocytosis and stimulate a weak response resulting from a lack of T-cell involvement. Contrary to this model, capsular polysaccharides from 23 serotypes of Streptococcus pneumoniae have been successfully used in a multivalent vaccine in the absence of a carrier protein," scientists in the United States report.

"Furthermore, type I pneumococcal polysaccharide (Sp1)...


Source: Vaccine Weekly (2009-04-29)

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