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Emory University



HIV handicaps itself to escape immune system pressure



April 29th, 2009

People with the ability to stave off AIDS for years after initial infection by HIV have been called "long-term non-progressors" or "elite controllers."

One component of this remarkable resistance comes from an individual's HLA genes. Long-term non-progressors tend to have HLA genes that help the immune system recognize and fight HIV more efficiently.

A team of researchers from the Emory Vaccine Center studying HIV-infected people with particularly effective HLA genes has observed how the virus mutates and evolves in response to immune pressure.

The observations, published in the Journal of Experimental Medicine, can provide...


Source: Vaccine Weekly (2009-04-29)

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