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Oral Squamous Cell Carcinoma
Studies from J.I. Kobayashi et al add new findings in the area of oral squamous cell carcinoma
May 6th, 2009
"Cytotoxic T lymphocytes (CTLs) play an essential role in immunologic responses for tumor rejection. In the past decade, various melanoma tumor-associated antigens (TAAs) have been identified, and several clinical trials of vaccination immunotherapy and adoptive immunotherapy using such antigens with or without adjuvants have had fascinating results," researchers in Sapporo, Japan report. "However, this has not been the case with oral squamous cell carcinoma (OSCC) because of the difficulty of establishing oral cancer cell lines and CTLs against autologous oral cancer cells. Therefore, few oral cancer antigens have been identified with such CTLs. We herein present the...
Source: Vaccine Weekly (2009-05-06)
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