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Rift Valley Fever
Reports from N. Lagerqvist and co-researchers add new data to research in rift valley fever
May 6th, 2009
"Affecting both livestock and humans, Rift Valley Fever is considered as one of the most important viral zoonoses in Africa. However, no licensed vaccines or effective treatments are yet available for human use," researchers in Umea, Sweden report. "Naked DNA vaccines are an interesting approach since the virus is highly infectious and existing attenuated Rift Valley Fever virus vaccine strains display adverse effects in animal trials. In this study, gene-gun immunisations with cDNA encoding structural proteins of the Rift Valley Fever virus were evaluated in mice. The induced immune responses were analysed for the ability to protect mice against virus challenge....
Source: Vaccine Weekly (2009-05-06)
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