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Vaccines



Researchers from University of Massachusetts, Department of Medicine report on findings in vaccines



May 6th, 2009

Researchers detail in 'Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists,' new data in vaccines. "beta-Glucans derived from fungal cell walls have potential uses as immunomodulating agents and vaccine adjuvants. Yeast glucan particles (YGPs) are highly purified Saccharomyces cerevisiae cell walls composed of beta1,6-branched beta1,3-d-glucan and free of mannans," scientists in the United States report.

"YGPs stimulated secretion of the proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) in wild-type murine bone marrow-derived myeloid dendritic cells (BMDCs) but did not stimulate...


Source: Vaccine Weekly (2009-05-06)

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