Cancer Vaccines

Researchers from University of Georgia report details of new studies and findings in the area of cancer vaccines

Published in Vaccine Weekly, May 6th, 2009

"Epithelial cancer cells often overexpress mucins that are aberrantly glycosyloted. Although it has been realized that these compounds offer exciting opportunities for the development of immunotherapy for cancer, their use is hampered by the low antigenicity of classical immunogens composed of a glycopeptide derived from a mucin conjugated to a foreign carrier protein," scientists in the United States report.

"We have designed, chemically synthesized, and immunologically evaluated a number of fully synthetic vaccine candidates to establish a strategy to overcome the poor immunogenicity of tumor-associated carbohydrates and glycopeptides. The compounds were also designed...

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Source: Vaccine Weekly (2009-05-06)

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