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Vaccine Weekly

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Herpesvirus



Data from P.D. Burbelo and colleagues advance knowledge in herpesvirus



May 6th, 2009

According to recent research published in the journal Clinical and Vaccine Immunology, "Highly quantitative and high-throughput serological tests for evaluation of humoral responses to herpes simplex virus 1 (HSV-1) and HSV-2 are not available. The efficacy of luciferase immunoprecipitation system (LIPS) assays for antibody profiling and serologic diagnosis of HSV-1 and HSV-2 infection was investigated using a panel of five recombinant HSV antigens."

"Plasma samples from subjects seropositive for HSV-1 and/or HSV-2 or seronegative for HSV-1 and HSV-2 that had previously been analyzed by Western blotting and the Focus Plexus immunoassay were evaluated. The LIPS...


Source: Vaccine Weekly (2009-05-06)

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