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Porcine Reproductive And Respiratory Syndrome
Studies from Department of Agriculture describe new findings in porcine reproductive and respiratory syndrome
May 6th, 2009
According to recent research published in the journal Clinical and Vaccine Immunology, "Control of virus replication initially depends on rapid activation of the innate immune response. Toll-like receptor (TLR) ligands are potent inducers of innate immunity against viral infections." "Porcine reproductive and respiratory syndrome virus (PRRSV), a positive-sense RNA virus, initiates infection in porcine alveolar macrophages (PAMs), elicits weak immune responses, and establishes a persistent infection. To understand the role of single-stranded RNA and double-stranded RNA (dsRNA) intermediates in eliciting host immunity, we sought to determine if TLRs, particularly...
Source: Vaccine Weekly (2009-05-06)
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