Immunization

New immunization findings from M. Humar and co-authors described

Published in Vaccine Weekly, May 6th, 2009

According to recent research published in the Journal of Cancer Research and Clinical Oncology, "Genetic vaccination by expression plasmids that encode mutant p53 was conducted to characterize exogenously induced anti-tumoral immunity in mice. Gene transfer was evaluated by reporter gene expression assays."

"The efficacy of genetic immunization was addressed by analysis of solid tumor outgrowth and the formation of metastases. Cell mediated immunity was determined by Cr-51-release cytotoxicity assays and adoptive lymphocyte transfer experiments. Genetic vaccination resulted in a persistent protection against the growth and metastasis of transplanted tumor cells....

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Source: Vaccine Weekly (2009-05-06)

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