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Rotavirus
Recent studies by K. Banyai and co-authors add new data to rotavirus findings
May 13th, 2009
"The rotavirus non-structural protein NSP4 has been implicated in a number of biological functions during the rotavirus cellular cycle and pathogenesis, and has been addressed as a target for vaccine development. The NSP4 gene has been classified into six genotypes (A-F)," investigators in Pecs, Hungary report. "A semi-nested triplex PCR was developed for genotyping the major human NSP4 genotypes (A-C), which are common in human rotavirus strains but are also shared among most mammalian rotavirus strains. A total of 192 previously characterized human strains representing numerous G and P type specificities (such as G1 P[8], G 1 P[4], G2P[4], G3P[3], G3P[8], G3P[9],...
Source: Vaccine Weekly (2009-05-13)
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