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Vaccine Weekly

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Hepatitis C Virus



Research from Emory University, Emory Vaccine Center provides new data on hepatitis C virus



May 13th, 2009

According to a study from the United States, "Adaptive T cell responses are critical for controlling infections with viruses such as HIV, HBV, and HCV. However, these responses must be carefully regulated because overly vigorous T cell activation can lead to excessive host tissue damage."

"T cell expression of the inhibitory receptor programmed death-1 (PD-1) and inhibition of effector T cells (Teffs) by CD4(+)Foxp3(+) Tregs are among the many described mechanisms for achieving a balanced immune response. Although the signals that contribute to Teff function are well understood, less is known about the signals controlling Tregs," wrote H. Radziewicz and colleagues,...


Source: Vaccine Weekly (2009-05-13)

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