Life Sciences

Studies from University of Otago yield new information about life sciences

Published in Vaccine Weekly, May 13th, 2009

"Orf virus (ORFV) is the type species of the genus Parapoxvirus, but little is known about the structure or morphogenesis; of the virus. In contrast, the structure and morphogenesis of vaccinia virus (VACV) has been extensively studied," scientists in Dunedin, New Zealand report.

"VACV has two main infectious forms, mature virion (MV) and extracellular virion (EV). The MV is wrapped by two additional membranes derived from the trans-Golgi to produce a wrapped virion (WV), the outermost of which is lost by cellular membrane fusion during viral egress to form the EV. Genome sequencing of ORFV has revealed that it has homologues of almost all of the VACV structural genes....

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Source: Vaccine Weekly (2009-05-13)

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