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Life Sciences
Studies from National Institutes of Health in the area of life sciences described
May 20th, 2009
"The inability to propagate obligate intracellular pathogens under axenic (host cell-free) culture conditions imposes severe experimental constraints that have negatively impacted progress in understanding pathogen virulence and disease mechanisms. Coxiella burnetii, the causative agent of human Q (Query) fever, is an obligate intracellular bacterial pathogen that replicates exclusively in an acidified, lysosome-like vacuole," scientists writing in the journal Proceedings of the National Academy of Sciences of the United States of America report. "To define conditions that support C. burnetii growth, we systematically evaluated the organism's metabolic...
Source: Vaccine Weekly (2009-05-20)
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