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Caliciviridae
Study findings from J.R. Topping et al broaden understanding of caliciviridae
May 20th, 2009
According to recent research published in the Journal of Virological Methods, "A one-step reverse transcription quantitative real-time polymerase chain reaction (RT-QPCR) method in combination with RNase treatment and low copy number samples was developed in order to examine the effect of temperature on the ability of virus capsids to protect their RNA content. The method was applied to a non-cultivable virus (GII.4 norovirus) and Feline calicivirus vaccine strain F-9 (FCV) which is often used as a norovirus surrogate." "Results demonstrated that FCV RNA is exposed maximally after 2 min at 63.3 degrees C and this correlated with a greater than 4.5 log reduction...
Source: Vaccine Weekly (2009-05-20)
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