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Vaccine Weekly

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Foot and Mouth Disease



New foot and mouth disease data have been reported by D. Dory and co-authors



May 20th, 2009

According to a study from Ploufragan, France, "To evaluate the feasibility of using pseudorabies virus (PrV) glycoprotein B (gB) as a carrier of foot and mouth disease virus (FMDV) antigens in DNA immunization, FMDV B- and T-cell epitopes were inserted either between the two B-cell epitopes of the N-term subunit of PrV-gB (BT-PrV-gB-N-term construct) or within the B-cell epitope of the C-term subunit of PrV-gB (BT-PrV-gB-C-term construct). Two animal experiments were performed, each with three injections of plasmids 2 weeks apart, followed by a booster inoculation of peptides corresponding to the FMDV epitopes."

"Control groups of pigs were injected with plasmids...


Source: Vaccine Weekly (2009-05-20)

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