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Vaccine Weekly

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HIV/AIDS



Studies from University of Cape Town in the area of HIV/AIDS published



May 20th, 2009

"Identifying the specific genetic characteristics of successfully transmitted variants may prove central to the development of effective vaccine and microbicide interventions. Although human immunodeficiency virus transmission is associated with a population bottleneck, the extent to which different factors influence the diversity of transmitted viruses is unclear," scientists writing in the Journal of Virology report.

"We estimate here the number of transmitted variants in 69 heterosexual men and women with primary subtype C infections. From 1,505 env sequences obtained using a single genome amplification approach we show that 78% of infections involved single...


Source: Vaccine Weekly (2009-05-20)

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