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University of Rochester Medical Center



Study reveals current multicomponent vaccines may need reworking



May 27th, 2009

Current strategies for designing vaccines against HIV and cancers, for instance, may enable some components in multi-component vaccines to cancel the effect of others on the immune system, eliminating their ability to provide protection, according to an article to be published shortly in the Proceedings of the National Academy of Sciences (PNAS). The authors also suggest, and successfully test, techniques that offer a solution to newly revealed mechanisms that enable some vaccine components to outcompete others.

Recognizing molecules as part one's self versus foreign invaders is the responsibility of the immune system. The adaptive component of that system creates a...


Source: Vaccine Weekly (2009-05-27)

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