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Cancer Vaccines
Researchers from Hokkaido University describe findings in cancer vaccines
May 27th, 2009
Current study results from the report, 'Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells,' have been published. "Unmethylated cytosine-phosphorothioate-guanine containing oligodeoxynucleotides (CpG-ODN) is known as a ligand of toll-like receptor 9 (TLR9), which selectively activates type-1 immunity. We have already reported that the vaccination of tumor-bearing mice with liposome-CpG coencapsulated with model-tumor antigen, ovalbumin (OVA) (CpG + OVA-liposome) caused complete cure of the mice bearing OVA-expressing EG-7 lymphoma cells," scientists writing in the journal Cancer Science...
Source: Vaccine Weekly (2009-05-27)
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