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Heparin



Research in the area of heparin reported from Duke University, Division of Hematology



May 27th, 2009

New investigation results, 'Optimization of a murine immunization model for study of PF4/heparin antibodies,' are detailed in a study published in Journal of Thrombosis and Haemostasis. "Heparin-induced thrombocytopenia (HIT) is a life-threatening thrombotic illness caused by drug-dependent antibodies recognizing complexes of platelet factor 4 (PF4) and heparin. Little is known about the immune pathogenesis of HIT, in particular factors influencing PF4/heparin antibody formation," scientists writing in the Journal of Thrombosis and Haemostasis report.

"To gain insight into the biologic basis of heparin sensitization, we have recently developed an animal...


Source: Vaccine Weekly (2009-05-27)

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