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Dementia



Researchers Surprised by Similar Structures in Sanfilippo Syndrome and Alzheimers Disease



May 27th, 2009

Researchers seeking to understand the causes of a rare genetic disease, Sanfilippo syndrome type B, were surprised to find protein aggregates, known as neurofibrillary tangles, that are usually seen in Alzheimer's and other forms of dementia, according to a study published May 4 in the Proceedings of the National Academy of Sciences.

The discovery, in a study conducted at the Los Angeles Biomedical Research Institute (LA BioMed) and the University of California, Los Angeles (UCLA), means that the childhood dementia often seen in Sanfilippo syndrome type B and other lysosomal storage diseases may have mechanisms similar to those found in Alzheimer's disease and other...


Source: Vaccine Weekly (2009-05-27)

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