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Immunization
Research from University of Florence provides new data about immunization
June 3rd, 2009
"Factor H-binding protein is a 27-kDa lipoprotein of Neisseria meningitidis discovered while screening the bacterial genome for vaccine candidates. In addition to being an important component of a vaccine against meningococcus in late stage of development, the protein is essential for pathogenesis because it allows the bacterium to survive and grow in human blood by binding the human complement factor H. We recently reported the solution structure of the C-terminal domain of factor H-binding protein, which contains the immunodominant epitopes," scientists in Sesto Fiorentino, Italy report. "In the present study, we report the structure of the full-length molecule,...
Source: Vaccine Weekly (2009-06-03)
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