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Stanford University Medical Center
Disruption of Immune-System Pathway Key Step in Cancer Progression, Stanford Study Shows
June 3rd, 2009
Human immune cells communicate constantly with one another as they coordinate to fight off infection and other threats. Now researchers at Stanford University’s School of Medicine have shown that muffling a key voice in this conversational patter is an early step in the progression of human cancers. Silencing an inter-cell signaling mechanism called the interferon pathway may be one way newly developing cancers gain the upper hand. It may also explain the immune dysfunctions seen in many cancer patients and why cancer immunotherapies are often ineffective. “Over half of cancer patients mount an immune response against their own cancer,” said hematologist Peter P. Lee,...
Source: Vaccine Weekly (2009-06-03)
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