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Falciparum Malaria
Researchers from Walter and Eliza Hall Institute of Medical Research describe findings in falciparum malaria
June 3rd, 2009
Research findings, 'Antibodies to reticulocyte binding protein-like homologue 4 inhibit invasion of Plasmodium falciparum into human erythrocytes,' are discussed in a new report. "Plasmodium falciparum invasion into human erythrocytes relies on the interaction between multiple parasite ligands and their respective erythrocyte receptors. The sialic acid-independent invasion pathway is dependent on the expression of P. falciparum reticulocyte binding protein-like homologue 4 (PfRh4), as disruption of the gene abolishes the ability of parasites to switch to this pathway," scientists in Parkville, Australia report. "We show that PfRh4 is present as an invasion...
Source: Vaccine Weekly (2009-06-03)
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