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Gene Therapy
Reports outline gene therapy study findings from Shandong University, Department of Hematology
June 3rd, 2009
Scientists discuss in 'Towards a novel vaccine against human cytomegalovirus based on a chimeric Ad5F35 adenovirus vector expressing the immunodominant antigenic domain 1 epitope' new findings in gene therapy. "Antibodies induced from glycoprotein B (gB) by antigenic domain (AD)-1 demonstrate broad neutralizing activity across different human cytomegalovirus (HCMV) types. This study aimed to prepare a novel HCMV vaccine using the modified adenoviral vector Ad5F35 to direct the expression of the conserved HCMV epitope AD-1 and to determine its transfer and expression in peripheral blood mononuclear cells (PBMCs)," researchers in Jinan, People's Republic of China report. ...
Source: Vaccine Weekly (2009-06-03)
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