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Immunization
Investigators at Naval Medical Research Center zero in on immunization
June 3rd, 2009
A report, 'Identification of cross-reactive epitopes on the conserved 47-kilodalton antigen of Orientia tsutsugamushi and human serine protease,' is newly published data in Infection and Immunity. "Orientia tsutsugamushi is the causative agent of scrub typhus. One of the protein antigens of this species, the conserved 47-kDa protein (HtrA), has been shown to induce an antibody response in patients and can provide protective immunity against live challenge by Orientia in mice," scientists writing in the journal Infection and Immunity report. "Pepscan experiments identified many peptide epitope clusters in different parts of this protein. The majority of the...
Source: Vaccine Weekly (2009-06-03)
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