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Vaccine Weekly

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Tuberculosis Vaccines



Study results from M. Domingo and colleagues broaden understanding of tuberculosis vaccines



June 3rd, 2009

Data detailed in 'Effectiveness and safety of a treatment regimen based on isoniazid plus vaccination with Mycobacterium tuberculosis cells' fragments: field-study with naturally Mycobacterium caprae-infected goats' have been presented. "The identification of a herd of goats with tuberculosis let us test a new treatment regimen against latent tuberculosis infection (LTBI). Using large animal experimental models allows a better approach to understanding human tuberculosis according to immunopathological parameters," investigators in Spain report.

"Based on an initial study showing a correlation between the ESAT-6-specific interferon (IFN)-gamma secretion and the severity...


Source: Vaccine Weekly (2009-06-03)

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