Epidemics

New epidemics research reported from P.T. Beernink and co-authors

Published in Vaccine Weekly, June 3rd, 2009

"Meningococcal epidemics in Africa are generally caused by capsular group A strains, but W-135 or X strains also cause epidemics in this region. Factor H-binding protein (fHbp) is a novel antigen being investigated for use in group B vaccines," scientists in the United States report.

"Little is known about fHbp in strains from other capsular groups. We investigated fHbp in 35 group A, W-135, and X strains from Africa. The 22 group A isolates, which included each of the sequence types (STs) responsible for epidemics since 1963, and 4 group X and 3 group W-135 isolates from recent epidemics had genes encoding fHbp in antigenic variant group 1. The remaining 6 W-135...

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Source: Vaccine Weekly (2009-06-03)

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