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Vaccine Weekly

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HIV/AIDS



Studies from AIDS Center have provided new data on HIV/AIDS



June 3rd, 2009

"We previously reported that cynomolgus monkeys vaccinated with the human immunodeficiency virus (HIV)-1 Tat protein controlled infection after challenge with the simian human immunodeficiency virus (SHIV) 89.6P(cy243) for up to 2 y of follow-up. To evaluate the breadth of the protective immunity elicited by the Tat protein, the vaccines along with the naive monkeys were intravenously rechallenged with a fivefold higher dose (50 MID50) of the same SHIV-89.6P(cy243)," scientists in Rome, Italy report.

"The vaccinated monkeys exhibited a statistically significant and long-lasting reduction of viral replication compared to control monkeys. This effect was associated with a...


Source: Vaccine Weekly (2009-06-03)

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