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Vaccine Weekly

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Life Sciences



Reports outline life sciences study results from Yale University, Department of Internal Medicine



June 3rd, 2009

New investigation results, 'Inhibition of neutrophil function by two tick salivary proteins,' are detailed in a study published in Infection and Immunity. "The saliva of hematophagous arthropods contains potent anti-inflammatory and antihemostatic activities that promote acquisition of the blood meal and enhance infection with pathogens. We have shown that polymorphonuclear leukocytes (PMN) treated with the saliva of the tick Ixodes scapularis have reduced expression of beta(2) integrins, impaired PMN adherence, and reduced killing of Borrelia burgdorferi, the causative agent of Lyme disease," scientists in the United States report.

"Here we describe two...


Source: Vaccine Weekly (2009-06-03)

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