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Vaccines
Research reports from Karolinska Institute Cancer Center provide new insights into vaccines
June 3rd, 2009
Research findings, 'Generation of a dendritic cell-based vaccine in chronic lymphocytic leukaemia using CliniMACS platform for large-scale production,' are discussed in a new report. According to recent research from Stockholm, Sweden, "We previously demonstrated that dendritic cells (DC) that have endocytosed apoptotic bodies of autologous leukemic cells (Apo-DC) can boost antileukemic T-cell responses. In this study, we report a description of the production procedure and product specification of the Apo-DC vaccine preparations for clinical use." "Enriched populations of CD14+ monocytic precursors and CD19+ leukaemic cells were obtained using CliniMACS technology from...
Source: Vaccine Weekly (2009-06-03)
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