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HIV/AIDS
New HIV/AIDS study findings have been reported by D. Promkhatkaew and co-researchers
June 10th, 2009
According to recent research published in the Southeast Asian Journal of Tropical Medicine and Public Health, "We have previously reported that live vector-based HIV-1 gag vaccine candidate using BCG as a vector was achievable in BALB/c mice. Although the gag-specific CTL induced by this live candidate vaccine is significantly high, persistence of CTL remains unclear." "Thus, efforts were made to explore the potential of recombinant Vaccinia virus DIs strain harboring the same HIV-1 CRF01_AE gag gene (rVaccinia/HIV-1gagE) present in the BCG construct, using different immunization routes. After one month following a single subcutaneous (s.c.) injection of...
Source: Vaccine Weekly (2009-06-10)
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