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Vaccine Weekly

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Tularemia



Researchers from University of Texas publish new studies and findings in the area of tularemia



June 10th, 2009

"Francisella tularensis is an intracellular gram-negative bacterium and the etiological agent of pulmonary tularemia. Given the high degrees of infectivity in the host and of dissemination of bacteria following respiratory infection, immunization strategies that target mucosal surfaces are critical for the development of effective vaccines against this organism," scientists in the United States report.

"In this study, we have characterized the efficacy of protective immunity against pneumonic tularemia following oral vaccination with F. tularensis LVS ( live vaccine strain). Mice vaccinated orally with LVS displayed colocalization of LVS with intestinal M cells, with...


Source: Vaccine Weekly (2009-06-10)

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