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HIV/AIDS
Report summarizes HIV/AIDS study findings from N. Scotti and co-researchers
June 10th, 2009
According to recent research from Portici, Italy, "Plants have been recognized as a promising production platform for recombinant pharmaceutical proteins. The human immunodeficiency virus Gag (Pr55(gag)) structural polyprotein precursor is a prime candidate for developing a HIV-1 vaccine, but, so far, has been expressed at very low level in plants." "The aim of this study was to investigate factors potentially involved in Pr55gag expression and increase protein yield in plant cells. In transient expression experiments in various subcellular compartments, the native Pr55gag sequence could be expressed only in the chloroplast. Experiments with truncated subunits suggested...
Source: Vaccine Weekly (2009-06-10)
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