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Inflammatory Bowel Disease
Recent findings from M. Papp and co-authors highlight research in inflammatory bowel disease
June 10th, 2009
"No clear guidelines for indirect immunofluorescence (IIF) detection and interpretation of antineutrophil cytoplasmic antibodies (ANCA) have been proposed for inflammatory bowel diseases (IBD). We evaluated the reliability of the combined use of ethanol- and formalin-fixed neutrophil substrates to identify atypical perinuclear ANCA (P-ANCA) by IIF under routine laboratory circumstances," scientists writing in the journal Clinical and Vaccine Immunology report. "A total of 204 IBD patients were assessed with four different fluorescent substrates in two distinct laboratories. Antibodies against myeloperoxidase, proteinase-3, and other specific granule proteins...
Source: Vaccine Weekly (2009-06-10)
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