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Acute Toxoplasmosis
Research reports from Gdansk University provide new insights into acute toxoplasmosis
June 10th, 2009
"A goal of the current study was to evaluate serological applications of Toxoplasma gondii GRA2 and rhoptry protein 1 (ROP1) antigens. Soluble recombinant GRA2 and ROP1 antigens as fusion proteins containing six histidyl residues at the N and C terminals were obtained using an Escherichia coli expression system," investigators in Gdansk, Poland report. "Purification by one-step metal affinity chromatography allowed recovery of milligram amounts of pure recombinant proteins per liter of culture. The usefulness of these antigens for diagnosis of human infections was tested on 167 serum samples obtained during routine diagnostic tests. A panel of 37 serum samples from...
Source: Vaccine Weekly (2009-06-10)
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