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Life Sciences
Findings from F. Takaiwa and co-authors broaden understanding of life sciences
June 10th, 2009
According to a study from Tsukuba, Japan, "A 7Crp peptide composed of seven major human T cell epitopes derived from the Japanese cedar pollen allergens Cry j 1 and Cry j 2 is an ideal tolerogen for peptide immunotherapy against Japanese cedar pollinosis. To maximize the accumulation level of the 7Crp peptide in transgenic rice seed, we tested endosperm specific promoters and intracellular localizations suitable for stable accumulation." "A 7Crp peptide carrying the KDEL ER retention signal directed by the 2.3-kb promoter of the glutelin GluB-1, which contains a signal peptide, accumulated at the highest level of about 60 mu g/grain. Notably, the 7Crp peptide...
Source: Vaccine Weekly (2009-06-10)
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