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Vaccine Weekly

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Vaccines



Studies from University of Illinois, Medical Department yield new information about vaccines



June 10th, 2009

According to a study from the United States, "It is postulated that unique nanoscale proteomic features of immunogen on vaccine particles may determine immunogen-packing density, stability, specificity, and pH-sensitivity on the vaccine particle surface and thus impact the vaccine-elicited immune responses. To test this presumption, we employed near-filed scanning optical microscopy (NSOM)- and atomic force microscopy (AFM)-based nanotechnology to study nano-structural and single-molecule force bases of Yersinia pestis (Y. pestis) V immunogen fused with protein anchor (V-PA) loaded on gram positive enhancer matrix (GEM) vaccine particles."

"Surprisingly, the...


Source: Vaccine Weekly (2009-06-10)

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